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General Information On Abraxane

Abraxane is usually used for treating breast cancer in its advanced stage. Paclitaxel belongs to the category of mitotic inhibitors that work by stopping the growth and spreading of cancer cells in the body. Your doctor will recommend you to buy Abraxane only after other drugs for treating cancer have been unsuccessful in achieving the desired results. Apart from that, the medicine can also be used for treating other cancers such as ovarian cancer, neck/throat cancer, head cancer, and lung cancer. The drug is available in the form of a protein bound suspension given to the patient in the form of an intravenous injection.

Side Effects for Abraxane

Vomiting, nausea, headache, mouth sores, diarrhea, muscle or joint pain, weakness, dizziness and numbness, and burning or tingling in the hands or feet are the common side effects of Abraxane. Temporary hair loss can also take place, but your hair will return to their normal growth pattern upon completion of the treatment. However, you should consult your doctor immediately if you are noticing signs of anemia like pale skin and unusual tiredness, easy bruising or bleeding, swelling, weakness, pain or redness in the arms or legs, swelling in the calves, and vision changes. Some serious but rare side effects of Abraxane include fainting, chest, left arm, or jaw pain, weakness on one side of the body, confusion, slurred speech, and severe headache. As this drug contains albumin, there are chances of contracting infections like hepatitis. Abraxane may also lead to hampered bone marrow function, resulting in a low WBC count. This condition can deteriorate your immunity and make you more susceptible to infections.

Precautions

As Abraxane can lower your immunity, you should try to stay away from sick people and pay special attention to your personal hygiene and cleanliness of your surroundings. Your doctor will not recommend you to buy Abraxane if you are already suffering from liver, heart, or kidney disease or if you have low marrow suppression. Whether you are a man or a woman, you should not become pregnant or father a child while you are taking Abraxane, as it can lead to birth defects in the unborn/newborn child. While taking the drug, you should use effective birth control methods, preferably of the barrier variant, such as condoms. Your doctor will test your blood often in order to make sure that you are getting better and that no other infections are present in your body. Therefore, you should not miss any of your follow-up visits and blood tests. As the drug causes dizziness, you should not do any such activity that calls for complete alertness, like driving a vehicle or operating a machine.

Abraxane Dosage

Abraxane 260 mg/m2 is given through an IV, which can take around 30 minutes to complete. The injection is given once in three weeks for patients who have breast cancer and have received (failed) chemotherapy before. If you are using the drug for treating moderate hepatic impairment, then you are advised to take Abraxane 200mg/m2, and for treating severe hepatic impairment, you are given Abraxane 130mg/m2.

Interactions

You should not take Abraxane with medicines like antibiotics, antidepressants, anti-fungal medications, blood thinners, other cancer medications, heart and blood pressure medications, HIV or AIDS medicines, seizure medications, and oral diabetes medications. You should also avoid taking Abraxane with drugs like osentan, imatinib, conivaptan, osentan, isoniazid, montelukast, rifampin, and selegiline.