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This item requires a prescription from your doctor.

General Information on Kytril

Kytril is the brand name for the Granisetron hydrochloride, a potent anti-emetic drug. It is used for the treatment and prevention of chemotherapy or radiation induced nausea and vomiting. Kytril belongs to the group of Serotonin – (5-HT3) receptor antagonists. You doctor may ask you to buy Kytril to prevent the early and late onset of nausea and vomiting. The medicine works by blocking the action of serotonin in the body. It is available in three forms - injectable (I.V), oral tablets, and oral solution. While Granisetron can be safely administered to adults, it’s not recommended for pregnant women and pediatric patients.

Side Effects for Kytril

Granisetron is known to cause mild to moderate side effects such as headache, dizziness, fever, pain/redness at the injection site, and diarrhea. However, most of these symptoms subside and do not need medical intervention. Although rare, this drug can also cause skin allergies such as rashes, itching, swelling of the face, tongue, or throat, etc. Some serious reactions reported with Kytril are chest pain, irregular heartbeat, severe dizziness, and abdominal pain. If you experience these or other serious symptoms while taking this medication, inform your doctor immediately.

Precautions

Before you buy Kytril, inform your doctor about your medical history. He/she may need to adjust your dosage if you are suffering from liver disorder/disease, electrolyte imbalance, heart rhythm disorder, or have a family history of Long QT disorder. The drug may not be suitable for you if you are allergic to Granisetron or other 5-FT3 blockers such as Dolasetron, Ondansetron, etc. The safety of this medicine has not been established for use by pregnant and lactating mothers, so in such cases, it is best to consult your health practitioner. The drug is usually taken an hour before the chemotherapy session. Inform your doctor if you forget to take your scheduled dose.

Kytril Dosage

For treating or controlling chemotherapy induced nausea, the usual dosage is Kytril 1 mg to be taken an hour before chemotherapy, and another 1 mg to be taken 12 hours after the session. The medicine can also be given in the IV form. The recommended injectable dosage is Kytril 10mcg/kg to be administered intravenously 30 minutes before the chemotherapy session. For adults undergoing radiation therapy, the dosage is Kytril 2 mg to be taken an hour before therapy. In case you have missed the dose or have not taken it at the scheduled time, inform your doctor about it, as he/she may want to reschedule the timing of chemotherapy.

Interactions

Kytril does not inhibit Cytochrome P-450 enzymes, so no confirmed drug interaction studies available in this regard. Granisetron injection can be used concurrently with Benzodiazepines, neuroleptics, and the anti-ulcer group of medications. Alcohol can increase the severity of side effects associated with this drug, so Kytril patients should limit their alcohol intake. Avoid using Granisetron with drugs that are known to prolong QT interval, as any such combination may cause serious clinical problems. In general, Kytril is considered a safe and non-reactive drug which can be concomitantly administered with most other medications.