Periostat (Doxycycline Hyclate) and/or equivalents
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General Information on PeriostatPatients suffering from gum disease are asked to buy Periostat. This drug is an antibiotic medicine used to treat periodontitis, a type of gum disease that arises from the accumulation of plaque. The antibiotic Doxycycline forms the chemical makeup of Periostat tablets. It is a Tetracycline antibiotic that fights bacteria within the body. Apart from periodontitis, Periostat may also be recommended for rosacea induced lesions, blemishes, and bumps. However, since it is a prescription drug, it should be used as per your doctor’s recommendation.
Side Effects of Periostat
The side effects of any medicine are different in people, but there are some common side effects that are visible in most Periostat patients. Headaches, a tendency to get common cold, and flu-like indications are the visible side effects of Periostat in at least one in ten users. Other side effects may include indigestion, diarrhea, sinus inflammation, rashes, toothache, pain in the joints, thrush infection, periodontal abscess, constipation, dry mouth, dizziness and general weakness. Some patients may not have any side effects at all, though most suffer from at least one side effect while using this medicine.
Let your doctor know all about your medical history, especially if you are prone to allergies. Allergies of any sort interfere with the doxycycline used to manufacture Periostat. Those suffering from kidney problems, liver disorders, and those prone to heartburn should have regulated doses of this medicine since these problems are aggravated with the use of Periostat.
Since Doxycycline makes a patient more prone to sunburn, those who have been recommended to buy Periostat should avoid sunlight as much as possible. While going out, they must use plenty of sunscreen and cover themselves with protective clothing. Prolonged use of Periostat can cause infection in the mouth, bladder, or vagina. Though these are rare symptoms, they are not totally unheard of.
Children up to the age of eight years should not be given Periostat since it can cause teeth problems as opposed to curing gum disease. Even in older children, caution must be observed. Since Periostat can also be present in the breast milk of a woman who takes this drug, the traces may be passed on from the mother to the child, and thus, breastfeeding women should not use Periostat.
Dosage of Periostat
Periostat is only recommended in controlled doses. Scaling and root planning procedures may be followed by a nine-month course of Periostat 20mg. Periostat 20mg is to be had twice a day at 12 hour intervals, preferably an hour or two before meals. According to the doctors’ suggestions, Periostat should be washed down with a lot of fluids to avoid irritating the esophagus and prevent ulcer formation.
Before you buy Periostat, let your doctor know if you are taking medication for cholesterol such as cholestyramine (Prevalite, Questran), isotretinoin (Accutane) , colestipol (Colestid) or tretinoin (Renova, Retin-A, Vesanoid). Those taking antacids or on bismuth subsalicylate containing drugs should also let their doctors know about the same. Other drugs that interact with Periostat include iron medicines, calcium supplements, magnesium supplements, vitamin compounds, blood thinners like Warfarin, and antibiotics such as penicillin and Oxacillin.
There are a few other rare drugs that interfere with Periostat usage. This is why it should never be used without consulting a doctor.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.