Zetia (Ezetimibie) and/or alternatives
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General Information On Zetia
Zetia is a unique type of medication for the treatment of high cholesterol. Unlike other cholesterol lowering medicines, known as statins, Zetia works in the digestive tract by blocking the absorption of cholesterol that you derive from food. It can be taken as a complement to other methods of lowering the cholesterol, like dieting or exercising and along with a statin. It can be taken with or without food any time if the day. It can also be taken both with and without a statin. You may require taking a blood test to check your liver before the start of treatment. It has been reported that people who added Zetia to their statin intake, reduced their bad cholesterol by an additional 25%.
Side Effects/Precautions For Zetia
There are a few side effects that have been noted while taking Zetia or Ezetimibe. Some of them are feeling of tiredness, joint pains, muscle aches, stomach pain, rash, nausea, diarrhea and dizziness. In some cases a tingling sensation, headache and gall stones have also been reported. If brand or generic Zetia is given along with a statin, it may cause muscle pain or weakness. In case of any of these side effects, inform your doctor immediately. The Zetia drug has not been known to prevent a heart attack or heart disease.
Ezetimibe is a prescription medication and should not be taken by anyone who is allergic to any of the ingredients. While on a treatment plan of brand or generic Zetia, it is equally important that you incorporate a healthy diet and an exercise plan so that both these work together with the medication to give you optimum benefit.
Zetia is available as a 10 mg tablet. The normal recommended dosage of this drug is 10 mg once every day. In a Concomitant Lipid Lowering Therapy, the dosage is administered with a statin or a fenofibrate in patients with primary or mixed hyperlipidemia. When co administered with Bile Acid Sequestrants, the dosage of this drug should be either 2 to 4 hours before or 2 to 4 hours after the administration of a bile acid sequestrant. In patients with Hepatic Impairment, Renal Impairment and Geriatric patients, there is no need for change in Zetia dosage.
Why Buy Zetia From Pharmacy RX World?
When you buy Zetia 10 mg from us, we can assure you of a lower price than any other pharmacy along with a free refill reminder service.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.