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Prempro (Estrogens, Conjugated/Medroxyprogesterone Acetate) and/or alternatives

Brand Name Options
  1. Buy Prempro

    Prempro 0.3/1.5mg

    Marketed as Premique Low Dose in European Union

    Manufactured by: Pfizer Ltd

    Product of United Kingdom. Shipped from United Kingdom

    RxPrescription Required

Generic OptionsWhat is a Generic?

No Generic Alternative.

Please note that the country, manufacturer, and/or shipping country may vary depending on availability. All trademarks and registered trademarks are the property of their respective owners.

General Information on Prempro

Prempro is prescribed for the treatment of menopause symptoms such as vaginal dryness, hot flashes, irritation, burning, and osteoporosis. Prempro is a combination of two generic medications – conjugated estrogens and medroxyprogesterone. Estrogen is a hormone that is produced by the ovaries and is required for the regulation of certain processes in a woman’s body. Medroxyprogesterone, also referred as progesterone, is one of the hormones that the body needs to regulate menstruation and ovulation.

You can buy Prempro as an oral tablet. You must not buy Prempro to treat or prevent heart disease or dementia.

Side Effects for Prempro

Allergic reactions may occur after taking Prempro. The symptoms of an allergic reaction are difficulty in breathing, swelling of the face, lips, tongue or throat, and formation of hives. Stop taking Prempro and seek emergency medical help if you notice any of these symptoms.

Other serious side effects may also occur after taking Prempro. Contact your doctor immediately if you experience any of the following – numbness or weakness in one side of the body, pain or swelling in the lower leg, sudden and severe headaches, chest pain, heavy feeling in the chest, and pain that spreads from the chest to the arm or shoulder. You should also inform your doctor if you experience migraine headaches, stomach aches, confusion, or breast lumps after taking Prempro.

Mild side effects of Prempro include mild nausea, bloating, stomach pain, vomiting, freckles, breast pain, swelling or tenderness, acne, and darkening of facial skin. Some more minor side effects are – changes in weight, increase in hair growth, vaginal itching, and changes in the menstrual cycle, reduced sex drive, headache, dizziness, fatigue, and nervousness.


Inform your doctor if you have a history of heart attack, blood clots or stroke, liver disease, undiagnosed vaginal bleeding, porphyria, gall bladder disease, hysterectomy, breast cancer, uterine cancer, or any other hormone-associated cancer. You may not be able to buy Prempro if you suffer from any of the above medical conditions.

Tell your doctor if you suffer from high blood pressure, cardiovascular disease, asthma, epilepsy, diabetes, migraine, under-active thyroid, high cholesterol or triglycerides, or endometriosis. Your doctor may change your dosage requirements if you suffer from any of the medical conditions given above.

Prempro Dosage

Prempro must be prescribed by a doctor and it is imperative that you follow your treatment schedule. Do not increase, decrease, or abruptly stop the medication on your own. This may have a serious negative effect on your health. Prempro is available in Prempro 0.3mg/1.5mg, Prempro 0.45mg/1.5mg, Prempro 0.625mg/2.5mg and Prempro 0.625mg/5mg tablets. Your doctor will decide which strength is appropriate for you. Prempro is usually taken once daily.

If you need to undergo any surgery during the treatment, tell your doctor that you are taking Prempro. Your doctor may advise you to stop Prempro medication for a short period of time.


Inform your doctor about all the prescription medications and over-the-counter medications that you are taking. The medications that require special mention are – Carbatol, Tegretol, Luminal, Solfoton, Norvir, Rifadin, Rifater, Rimactane Rifamate, Nizoral and Sporanox. These medications, along with antibiotics like Biaxin, Erythrocin and Nizoral, may interact with Prempro.

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