Prempro (Estrogens, Conjugated/Medroxyprogesterone Acetate) and/or alternatives
No Generic Alternative.
Please note that the country, manufacturer, and/or shipping country may vary depending on availability. All trademarks and registered trademarks are the property of their respective owners.
General Information on Prempro
Prempro is prescribed for the treatment of menopause symptoms such as vaginal dryness, hot flashes, irritation, burning, and osteoporosis. Prempro is a combination of two generic medications – conjugated estrogens and medroxyprogesterone. Estrogen is a hormone that is produced by the ovaries and is required for the regulation of certain processes in a woman’s body. Medroxyprogesterone, also referred as progesterone, is one of the hormones that the body needs to regulate menstruation and ovulation.
You can buy Prempro as an oral tablet. You must not buy Prempro to treat or prevent heart disease or dementia.
Side Effects for Prempro
Allergic reactions may occur after taking Prempro. The symptoms of an allergic reaction are difficulty in breathing, swelling of the face, lips, tongue or throat, and formation of hives. Stop taking Prempro and seek emergency medical help if you notice any of these symptoms.
Other serious side effects may also occur after taking Prempro. Contact your doctor immediately if you experience any of the following – numbness or weakness in one side of the body, pain or swelling in the lower leg, sudden and severe headaches, chest pain, heavy feeling in the chest, and pain that spreads from the chest to the arm or shoulder. You should also inform your doctor if you experience migraine headaches, stomach aches, confusion, or breast lumps after taking Prempro.
Mild side effects of Prempro include mild nausea, bloating, stomach pain, vomiting, freckles, breast pain, swelling or tenderness, acne, and darkening of facial skin. Some more minor side effects are – changes in weight, increase in hair growth, vaginal itching, and changes in the menstrual cycle, reduced sex drive, headache, dizziness, fatigue, and nervousness.
Inform your doctor if you have a history of heart attack, blood clots or stroke, liver disease, undiagnosed vaginal bleeding, porphyria, gall bladder disease, hysterectomy, breast cancer, uterine cancer, or any other hormone-associated cancer. You may not be able to buy Prempro if you suffer from any of the above medical conditions.
Tell your doctor if you suffer from high blood pressure, cardiovascular disease, asthma, epilepsy, diabetes, migraine, under-active thyroid, high cholesterol or triglycerides, or endometriosis. Your doctor may change your dosage requirements if you suffer from any of the medical conditions given above.
Prempro must be prescribed by a doctor and it is imperative that you follow your treatment schedule. Do not increase, decrease, or abruptly stop the medication on your own. This may have a serious negative effect on your health. Prempro is available in Prempro 0.3mg/1.5mg, Prempro 0.45mg/1.5mg, Prempro 0.625mg/2.5mg and Prempro 0.625mg/5mg tablets. Your doctor will decide which strength is appropriate for you. Prempro is usually taken once daily.
If you need to undergo any surgery during the treatment, tell your doctor that you are taking Prempro. Your doctor may advise you to stop Prempro medication for a short period of time.
Inform your doctor about all the prescription medications and over-the-counter medications that you are taking. The medications that require special mention are – Carbatol, Tegretol, Luminal, Solfoton, Norvir, Rifadin, Rifater, Rimactane Rifamate, Nizoral and Sporanox. These medications, along with antibiotics like Biaxin, Erythrocin and Nizoral, may interact with Prempro.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.