Amitiza (Lubiprostone) and/or alternatives
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General Information On Amitiza
Amitiza is a medicine which helps to keep chronic constipation (especially idiopathic constipation) in control. It is also useful in treating irritable bowel dysfunction caused due to constipation or as a side effect of opioid. This medicine works as an activator for chloride channel. It enables your intestines to produce the required amount of fluids that are necessary for easy intestinal muscle movement and bowel movements.
Side Effects/Precautions for Amitiza
The chemical name for this medicine is Lubiprostone and its ingredients are: Lubiprostone, gelatin, sorbitol, Yellow D and C (Number 10), purified water, Red FD and C (Number 40) and triglycerides of medium -chain category. Nausea and diarrhea are the two major side effects of generic Amitizia. Other common side effects of this medicine include headache, stomach pain, anxiety, cold and cough and pain in the joints. Some patients might also get swelling in the hands or feet as a side effect of this medicine. The Amitiza drug should be taken strictly as per the prescription as an overdose can cause breathing problems, severe diarrhea, hot flashes, and lightheadedness. Many patients may also lose consciousness due to an overdose.
Those who are already suffering from severe diarrhea or gastrointestinal tract blockage should avoid taking this medicine. The Amitiza drug is also not good for pregnant women. Generic Amitizia falls under category C and can have fatal repercussions on the fetus. If you get pregnant while you are on this drug; immediately discontinue the drug and consult your doctor.
For the treatment and management of chronic idiopathic constipation, 24 mcg of Amitiza is administered orally, two times a day. For the treatment and management of irritable bowel syndrome 8 mcg of the drug is administered orally, two times a day. The drug can be taken with food as well as water. Your physician should assess you on a regular basis, to determine if Amitiza treatment needs to be continued further or not. Also, based on your response to the treatment, your physician may adjust the doses (either increase or decrease the doses) of the drug.
Why Buy Amitizia From Pharmacy RX World?
Be it Amitiza 8 mcg, 24 mcg or any other medicine; we are never out of stock. We are also approved by pharmaceutical accreditation organizations and are well known for strict adherence to prescription fulfillment standards. You can buy Amitizia from us and be sure that you are in safe hands.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.