Creon 10 (Pancreatic Digestive Enzymes) and/or equivalents
No Generic Alternative.
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General Information on Creon 10
Creon 10 is a combination of three human proteins or enzymes- namely, protease, lipase, and amylase. The pancreas produces these enzymes naturally, and they play an important role in the digestion of fats, sugars and proteins. Creon 10 is used for replacing these enzymes if a person is suffering from a condition that causes a lack of these enzymes. Such conditions include chronic pancreatic inflammation, blockage in the pancreatic ducts, and cystic fibrosis. The generic name of Creon 10 is Pancrelipase, and it belongs to the therapeutic category of drugs named enzyme replacement medicines. This drug is available in an oral capsule form and works by breaking down fats, starches, and proteins from the food into smaller units so that they can be easily absorbed by the intestines. Your doctor may also advise you to buy Creon 10 if you have recently got your pancreas surgically removed.
Side Effects for Creon 10
The possible side effects that you may experience during Creon 10 treatment include diarrhea or constipation, vomiting, stomach cramps, gas, bloating, anus irritation, rash, headache, tarry or black stools, joint pain, swelling in the joints, or stomach pain. Most of these are short-lived and improve on their own as your body gets adjusted to the drug. However, if any of these worsen or persist, you should stop taking the capsules and seek medical help.
You should also stop taking Creon 10 if you develop an allergic reaction to it. An allergic reaction can be identified by hives, difficulty breathing, severe dizziness, or swelling or itching of the face, throat, lips, or tongue.
Special tests need to be conducted if you are suffering from a kidney disease, gout, chronic pancreatic disease, or if you have a history of intestinal blockage. While taking the Creon 10 capsules, you should swallow them immediately, as allowing them to stay on in your mouth for a long time can lead to oral irritation. Also do not crush the drug and inhale it, as doing so may irritate your nose and lungs. If the capsules remain in contact with your skin for a few minutes, they may even cause a skin rash in the area. Pregnant women and breastfeeding mothers should not take these capsules, as they may cause harm to the unborn or nursing baby. You should immediately contact your doctor if you become pregnant during Creon 10 treatment.
Creon 10 Dosage
Initially, your doctor will advise you to take 1-2 capsules per snack or meal. However, if the patient is less than 6 years of age, he/she should be given only one capsule per snack or meal. Store the capsules between 15º to 30ºC, away from heat and moisture. The duration for which Creon 10 needs to be taken is not constant, as it depends on several conditions such as your age, medical conditions, and response to treatment. You will be advised to take Creon 10 till your disease has been cured or until the desired effects are achieved. When it comes to stopping Creon 10 use, your doctor will taper off the dosage gradually.
Before you buy Creon 10 capsules, you should inform your doctor about all the prescription and non-prescription medicines you are taking at present, including herbal products and health supplements.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.