Accuretic (Quinapril Hydrochloride/Hydrochlorothiazide) and/or alternatives
No Generic Alternative.
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General Information On Accuretic
Accuretic is a combination of two medicines, hydrochlorothiazide and quinapril, and is used to treat hypertension (high blood pressure). This drug falls under a class of drugs known as angiotensin converting enzymes, or ACE. Like other drugs in its class, Accuretic relaxes blood vessels and improves the flow of blood. The generic name of this drug is hydrochlorothiazide and quinapril.
Side Effects for Accuretic
Accuretic may cause side effects in certain rare cases. Before you start treatment, discuss the potential risks with your doctor. Some of the common and mild side effects of Accuretic are dizziness, insomnia, muscle pain, back pain, headache, running nose, stomach upset, constipation, diarrhea, increased sweating, cough, or mild skin rash. In most cases, the above symptoms are mild and temporary. With that said, you should consult your doctor if any of the aforementioned symptoms become bothersome or persist for a long time.
Consult your doctor if you experience any of the following serious side effects: chills, fever, flu symptoms, body aches, less than normal urination, light-headedness, drowsiness, weakness, shortness of breath, unexpected and sudden weight gain, swelling, dry mouth, increased thirst, nausea, vomiting, vision problems, eye pain, yellowing of skin or eyes, symptoms of low potassium (muscle weakness, uneven heart rate, limp feeling, increased urination, extreme thirst, or leg discomfort), or symptoms of high potassium (weak pulse, tingly feeling, slow heart rate, or muscle weakness).
Stop your medication and seek emergency medical help if you experience any of the following symptoms after taking Accuretic, as they are the signs of an allergic reaction: trouble breathing, shortness of breath, wheezing, hives, skin rashes, itching, or swelling of your lips, tongue, throat, or face.
You should not buy Accuretic if you are allergic to quinapril or hydrochlorothiazide or other ACE inhibitors such as ramipril, enalapril, fosinopril, captopril, moexipril, trandolapril, lisinopril, or moexipril.
Before starting treatment, you must tell your doctor about your medical history, especially if you have/have had any of the following: gout, diabetes, heart failure, liver disease, glaucoma, kidney disease, or lupus.
The drug is contraindicated in pregnant women as it can harm an unborn child. Do not buy Accuretic if you are pregnant. Inform your doctor as soon as possible if you are found to be pregnant while still on Accuretic. The safety of this drug in breastfeeding women has not been established. If you are breastfeeding a child, do not use Accuretic unless otherwise specified by your doctor.
Depending on your condition, your medical history, and response to treatment, your doctor will select and prescribe the dosage of this medication of you. The recommended dosage for the treatment of hypertension is between Accuretic 10mg/12.5mg to Accuretic 20mg/25mg daily. Accuretic is available in three strengths, Accuretic 10mg//12.5mg, Accuretic 20mg/12.5mg and Accuretic 20mg/25mg.
Certain drugs such as narcotic pain medicines, sleeping pills, sedatives, muscle relaxants, antidepressants, and seizure medicines may cause serious side effects when taken along with Accuretic. In addition to the above, other drugs that are known to interact with Accuretic include the following: lithium, other hypertension medications, tetracycline antibiotics (such as tetracycline, doxycycline, or minocycline), colestipol, cholestyramine, NSAIDs (such as indomethacin, ibuprofen, aspirin, diclofenac, naproxen, celecoxib, and others), and diabetes medications.
Other drugs that are not listed above may also interact with Accuretic. That is why you should inform your doctor about all the drugs that you have taken or are still taking before you buy Accuretic.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.