Shipping Update – January 2022

Shipping times are now closer to normal. However, due to the latest outbreak of the highly contagious Omicron strain, we are anticipating some potential delays in our shipping times. We will provide updates as the situation changes.

Our normal shipping time averages 1 - 2 weeks. Shipments may now sometimes take an additional 2 – 4 weeks to arrive, depending on the source country of your order. Shipments from the United Kingdom and Canada are generally quicker than from other countries.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

We offer a shipping guarantee when you place an order with us. If your order does not arrive within 6 weeks from the date it was shipped, we will re-ship your order to you at no additional cost.

Call Center – New Hours effective January 17, 2022

Our new call center hours of operation are now 7:00 am – 7:00 pm Central Time, seven days per week.

These changes are due to staffing issues we are experiencing caused by the highly contagious Omicron variant. We anticipate that we will expand our call center hours again within the next 2 – 3 weeks.

If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health and safety of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We appreciate your business and thank you for your continued support.

Management and Staff
Pharmacy Rx World
FREE Shipping on all orders over $49 USD

Activella (Estradiol/Norethindrone Acetate) and/or alternatives

Brand Name Options
  1. Buy Activella

    Activella LD 0.5/0.1mg

    Marketed as Activelle LD in Canada

    Manufactured by: Novo Nordisk Canada Inc

    Product of Canada. Shipped from Canada

    RxPrescription Required

  2. Buy Activella

    Activella 1/0.5mg

    Marketed as Kliovance in European Union

    Manufactured by: Novo Nordisk

    Product of United Kingdom. Shipped from United Kingdom

    RxPrescription Required

Generic OptionsWhat is a Generic?

No Generic Alternative.

Please note that the country, manufacturer, and/or shipping country may vary depending on availability. All trademarks and registered trademarks are the property of their respective owners.

General Information On Activella

Activella is a combination of Norethindrone and Estradiol used for treating certain menopause symptoms like hot flushes. Estradiol is a form of estrogen used for maintaining a woman’s reproductive system. Norethindrone is a form of progesterone, which has an important role in the regulation of menstruation and ovulation. Your doctor may also ask you to buy Activella in order to treat vaginal problems like itching, dryness, or burning in or around the vagina and burning or any other difficulty during urination. Activella is available in the form of 0.1/ 0.5mg and 0.5/0.1mg strength tablets.

Side Effects for Activella

Lightheadedness, dizziness, stomach upset, headache, irritability, bloating, nausea, changes in sleep patterns, weight changes, increased or decreased libido, changes in vaginal discharge, and breast tenderness are some common side effects of Activella. You need to contact your doctor if you witness any breast lumps, mental or mood changes, nipple discharge, swelling on the hands or feet, yellowing of the eyes or skin, unusual vaginal bleeding, seizures, and signs of diabetes like increased urination and thirst. Sometimes, Activella can also lead to heart attacks, blood clots, and strokes. In this case, you should watch out for symptoms like chest, left arm, or jaw pain, severe headache, confusion, weakness on one side of the body, slurred speech, calf pain or swelling, coughing up of blood, trouble breathing, sudden vision changes, sudden fainting, or dizziness.


You should not use Activella if you are suffering from breast, uterine, or ovarian cancer, liver disease, unknown vaginal bleeding, or if you have a history of heart attack, blood clots, or strokes. You should also inform your doctor if you have a personal or family history of asthma, seizures, diabetes, heart disease, migraine, kidney disease, abnormal levels of calcium in the blood, an underactive thyroid, cholestatic jaundice, toxemia, uterine fibroids, high triglyceride or cholesterol levels, obesity, gallbladder disease, lupus, or a blood disorder like porphyria. As Activella can cause skin patches, you should avoid direct exposure to sunlight and wear protective clothing if you have to go out. Avoid using tobacco or smoking cigarettes as doing so can further increase your risks of blood clots, strokes, heart attacks, or high blood pressure. This drug is also not recommended for pregnant women and breastfeeding mothers.

Activella Dosage

If you have mild or severe vasomotor symptoms associated with menopause, you should take an initial dose of Activella 1.0/0.5mg or Activella 0.5/0.1mg. If you are using it to prevent postmenopausal osteoporosis, you will be recommended to take Activella 1.0/0.5mg or Activella 0.5/0.1mg. For treating vaginal and vulvar atrophy, you will need to take Activella 1.0/0.5mg. The tablet has to be taken only once a day.


Before taking Activella, you should tell your doctor if you are taking an anticoagulant or blood thinner like warfarin. You should also not take Activella with exemestane or anastrozole, as serious side effects may occur. Your doctor will not recommend you to buy Activella if you are already taking corticosteroids, drugs that affect liver enzymes, macrolide antibiotics, rifamycins, azole anti-fungals, anti-seizure medications, and St. John’s Wort.

IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.