Actoplus Met (Pioglitazone Hydrochloride/Metformin Hydrochloride) and/or alternatives

General Information On Actoplus Met

Actoplus Met is a combination of two medicines used for controlling high blood sugar levels in people suffering from Type 2 diabetes. This eventually helps in preventing other complications like kidney damage, nerve problems, blindness, sexual dysfunction, and loss of the limbs. The medicine is a combination of metformin hydrochloride and pioglitazone hydrochloride; the latter belongs to the category of drugs termed as glitazones or thiazolidinediones, which help your body respond properly to naturally produced insulin. Metformin also reduces the amount of sugar that is produced by the liver and absorbed by the intestines and stomach. You can buy Actoplus Met in the form of oral tablets, but do note that this drug cannot be used for treating Type 1 diabetes or by people who are already taking insulin injections regularly.

Side Effects for Actoplus Met

Some common side effects that you may experience after using Actoplus Met are stomach upset, muscle pain, tooth problems, metallic taste in the mouth, diarrhea, vomiting, nausea, sore throat, weight gain, and weakness. Pioglitazone can sometimes lead to liver disease, for which you have to be cautious about symptoms like yellowing of the skin or eyes, dark urine, and persistent nausea or vomiting. Actoplus Met can also cause congestive heart failure, which can be identified by unusual tiredness, trouble breathing, sudden weight gain, and swelling of the hands or feet. Metformin can also cause a fatal condition known as lactic acidosis. You should watch out for symptoms like difficult or fast breathing, severe drowsiness, cold or bluish skin, unusual tiredness, stomach pain, diarrhea, chills, and muscle pain. You should also inform your doctor if you suffer from blurred vision or if you have a bone fracture.

Precautions

Lactic acidosis, a side effect of Actoplus Met, is more common in patients who are already suffering from a condition like liver or kidney disease, serious infection, congestive heart failure, heart attack, or stroke. You should avoid alcohol during Actoplus Met treatment and drink lots of fluids in order to prevent dehydration, which may worsen the side effects of the drug. This drug does not cause low blood sugar, but the same can occur if you are using it with other diabetes medicines like insulin or sulfonylurea. If you are to undergo a CT scan or X-ray and if a dye is going to be injected in your veins, your doctor may advise you to stop using Actoplus Met temporarily. So, before going for such a test, you should inform your doctor or laboratory personnel that you are taking Actoplus Met, so that he/they can take the necessary precautions.

Actoplus Met Dosage

You will initially be advised to take pioglitazone 15 to 30mg and Metformin 850 to 1000 mg every day. The medicine has to be taken along with food, and your doctor can increase the dose depending on how you respond to the treatment. However, the daily dose should not exceed pioglitazone 45mg and metformin 2550mg per day.

Interactions

Your doctor will not recommend you to buy Actoplus Met if you are already taking NSAIDs, seizure medicines, diuretics, steroids, blood pressure or heart medicines, phenothiazines, thyroid medicines, birth control pills, diet pills, and drugs for treating asthma, allergies, and cold.

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