Advantage Multi (Imidacloprid/Moxidectin) and/or alternatives
No Generic Alternative.
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General Information On Advantage Multi
Advantage Multi is used for preventing heartworm in dogs and cats, for treating fleas, hookworms, roundworms and ear mites in cats, and hookworms, whipworms, roundworms and fleas in dogs. Its generic name is Imidacloprid/Moxidectin, and it belongs to the category of Ecoparasiticides. This medicine is available in a liquid application form. Imidacloprid works by attaching itself to the nicotinic acetylcholine receptors of the fleas’ nervous systems, so that their ability of transmitting acetycholine is inhibited and they get paralyzed and eventually die. Moxidectin in the drug opens chloride channels, so that an irreversible resting state is induced, leading to the parasites getting paralyzed and eventually dying or leaving the host.
Side Effects for Advantage Multi
Some of the commonly experienced side effects of Advantage Multi noticed in dogs include lethargy or hyperactivity, decreased appetite, or licking or scratching the site of application. In cats, increased drinking or salivation, agitation, coughing, excessive grooming, and other changes in behavior may be noticed. These are common side effects of the Advantage Multi, and its use should not be discontinued if any of these are experienced. However, some of the serious side effects of Advantage Multi include pale gums, seizures, cold limbs, diarrhea, coma, shock, vomiting, swelling, or hives. If the pet experiences any of these serious side effects, immediate medical help should be sought. If the pet accidentally ingests the medicine by licking the application site, it may experience generalized muscle tremors, panting, poor coordination, dilated pupils, depression, and excessive salivation.
Advantage Multi is only meant for dogs over 7 weeks of age and cats over 9 weeks of age. Geriatric cats should not be treated with this drug. You should not apply this medicine on your pet if its skin is already broken or irritated or if it is underweight or ill. Use Advantage Multi with caution on pregnant, lactating, or breeding animals. After applying the drug on your pet’s body, make sure that it does not lick the application site. Also keep it away from other pets so that it does not come in contact with them, as doing so may increase risks of accidental ingestion or the spread of an infection. If your pet is sensitive to avermectin, it may suffer from a coma.
Advantage Multi Dosage
The dosage given to an animal largely depends on its size and weight. For example, a dog weighing 3 to 9 pounds will be given Advantage Multi 40/10mg. Apply the drug on your pet’s body once a month, only after giving it a bath. Advantage Multi needs to be applied on the pet’s body directly on the skin after parting the hair between the shoulder blades and its back. Keep the pet away from other animals and children for at least 30 minutes after applying Advantage Multi.
Tell the veterinarian about all the herbal products and medicinal products you are using or have used to treat your pet. Also tell him/her about all the topical applications and injections your pet has already received.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.