Aptivus (Tipranavir) and/or alternatives
No Generic Alternative.
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General Information on Aptivus
Aptivus is a prescription drug approved to treat AIDS and HIV. Doctors typically administer this drug in combination with Ritonavir, another HIV drug. Aptivus belongs to the class of drugs known as protease inhibitors. The drug works by stopping the HIV virus from spreading to uninfected body cells. It is available in both capsule and oral solution form. If you are HIV positive, the doctor may suggest that you buy Aptivus to treat the disease.
Side Effects for Aptivus
A few patients using Aptivus suffer from some side effects, most of which are mild and can be easily treated. Only about 2% of the patients using Aptivus experience serious side effects such as sudden headache, unexplained bleeding, problems with vision, difficulty while talking, nausea, stomach ache, drastic loss of appetite, fever, black stools or dark urine, and jaundice. If you suffer from any of these side effects, you must quickly seek medical attention.
The minor and more common side effects of Aptivus are mild stomach pain, tiredness or drowsiness, change in location or shape of body fat in the neck, breasts, and legs, constant thirst, and fever.
Using Aptivus can lead to some serious consequences if you don’t know the right way to use it. Before using the drug, you must discuss the risks, benefits, and precautionary measures with your doctor. You must avoid using a smaller or larger dosage of the drug or for a longer period than recommended by your doctor. You must also be sure that you take Ritonavir along with Aptivus unless your doctor recommends otherwise. While taking the capsule, you must avoid breaking or chewing the capsules; swallow it completely with food. Avoid taking the drug if you have any liver related diseases including liver failure, cirrhosis, and hepatitis. Don’t use Aptivus without your doctor’s consent if you have diabetes, high blood pressure, allergy to certain preservatives and foods, or if you are pregnant and breastfeeding.
Doctors prescribe different Aptivus doses for different patients depending on their age and the way they respond to the drug. For children, the recommended Aptivus dosage is decided based on their height and weight. Usually, doctors recommend a 500 mg dose to adults, combined with 200 mg of ritonavir twice a day. To gain maximum benefits from the drug, you must strictly adhere to the dosage recommended by the doctor. It is also advisable to take your Aptivus dose at fixed hours every day. If you skip any dose or if you suspect an overdose, consult your doctor immediately.
If you are using some other drugs along with Aptivus, the combination of these medicines may lead to drug interactions. This may reduce the effectiveness of the drugs and also increase the risk of adverse side effects. Clinical studies suggest that Aptivus may potentially with certain oral diabetes medicines, calcium channel blockers, antidepressants, and hormonal contraceptive drugs. In addition, Aptivus also interacts with certain herbal products and vitamin supplements. When you buy Aptivus, make sure that you provide your doctor a list of all the other medicines you are using. The doctor may review the list and suggest ways to use Aptivus safely.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.