Aromasin (Exemestane) and/or alternatives

General Information On Aromasin

Aromasin is prescribed to treat specific types of breast cancer in women after menopause. The generic name of the drug is Exemestane and it works by decreasing the amount of estrogen in body which in turn slows down or reverses the growth of breast cancer cells. Aromasin is an aromatase inhibitor, which means it blocks the aromatase enzyme (found in the skin, muscles, fat and breasts). The aromatase enzyme is used to convert androgens into estrogen. Cancer cells that are dependent on estrogen shrink in the absence of it, and so, their growth is slowed down.

The medication is extremely useful in treating breast cancers that grow fast due to estrogen. The medication is not prescribed for women of childbearing age, and you should buy Aromasin only if the doctor has recommended it to you. The drug is found effective where drugs like Tamoxifen don't work to slow down the growth of cancer cells.

Side Effects for Aromasin

Some people may experience side-effects after taking this medication. The side-effects are reversible though, which means they vanish after therapy is completed. Some side-effects that you may experience are nausea (mild), anxiety, shortness of breath, depression, bone pain, hot flashes, insomnia and fatigue. You may also experience other side-effects other than those mentioned after taking the drug. You need to inform your doctor about any side-effects you experience or notice after taking the drug.

Precautions

Aromasin tablets are not suitable for pregnant women as it can harm the fetus. Women who are breastfeeding should not take Aromasin. Those planning to have a baby should not take the medication either. It is necessary to consult your doctor and discuss if it would be safe to conceive or become pregnant after therapy is completed. Pregnant women or women trying to conceive should tell their doctor before they are recommended a dose of Exemestane. You should tell your doctor about different medications you take that includes prescribed medications, over the counter medication or herbal remedies to avoid possible side-effects.

Aromasin Dosage

The medication is available in tablet form. Doctors generally recommend a dose of one Aromasin 25 mg tablet a day after a meal in the early and advanced stages of breast cancer. The medication dosage is modified for patients receiving Aromasin with a potent CYP 3A4 inducer such as Phenytoin or Rifampicin. The dosage is doubled for such patients, and they are recommended a once daily dosage of 50 mg (2 tablets of Aromasin 25 mg) after a meal. The dosage of Aromasin is recommended by the doctor and in some cases, he/she may recommend a high dosage of 200 mg of the medication. The drug is effective in treating breast cancer in certain cases. It is important for you to consult your doctor to determine if Aromasin is right for you and to obtain a prescription before you buy Aromasin.

Interactions

Aromasin may interact with specific medications such as estrogen drugs, oral contraceptives, and anticonvulsants such as Fosphenytoin (Cerebyx), Pentobarbital (Nembutal), Primidone (Mysoline), Oxcarbazepine (Trileptal) and Phenobarbital (Luminal). This interaction can decrease the effectiveness of the medication, and your doctor may feel the need to increase the dosage of Aromasin tablets. You need to inform your doctor about every medication you take such as prescribed and non-prescribed medicines and herbal medication to prevent any possible side-effects.

Aromasin is a hormone therapy drug. It is used in the treatment of progressive breast cancer in women who are in their post menopausal period. It is also used in women who have already taken tamoxifen treatments for cancer. The presence of estrogen in the body strengthens the breast cancer tumor. brand or generic Aromasin decreases the estrogen or hormone levels in the body by blocking the enzyme aromatase that converts the hormones developed in the adrenal glands into estrogen thereby restricting the growth of the tumor. Aromasin 25 mg is available only against the prescription of a doctor. This drug is suitable only for women who are in their post menopausal phase and are not taking any other hormone replacement therapy medicines as they also contain estrogen.

Side Effects/Precautions for Aromasin

Possible serious side effects of taking the Aromasin drug or Exemestane include hand or feet swelling, shortness of breath, headaches with aura and speech problems. This should be brought to the immediate attention of your doctor. The less serious side effects of brand or generic Aromasin include depression, nausea, insomnia and fatigue. This medicine may also lead to osteoporosis as it decreases the bone mineral density if taken for a long period.

Exemestane is not recommended for pregnant or breast feeding women. Before starting the dosage, ensure that you tell the doctor about any other drugs that you are on. The intake of this drug may harm your unborn baby, so take precautions to prevent pregnancy. Breast feeding is also not advisable. Discuss your allergies with your doctor to check if this medicine is suitable for you. Aromasin has to be taken in the respective dose which your doctor prescribes. It is taken orally once a day or as directed by your physician.

Aromasin Dosage

In the early stage and advanced stage of breast cancer the recommended dose of Aromasin is a 25 mg tablet. It is administered after a meal, once daily. In post-menopausal women who are in early stages of breast cancer, the drug should be continued even if there is no recurrence of cancer until the 5 years’ endocrine-adjuvant therapy is completed. Patients who are in the advanced stages of breast cancer must continue the treatment till improvement is evident. If a patient is on Aromasin along with other drugs like Phenytoin or Rifampicin then the recommended dose is 50 mg, administered after a meal once daily.

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