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Bonefos (Disodium Clodronate) and/or alternatives

Brand Name Options
  1. Buy Bonefos

    Bonefos 400mg

    Manufactured by: Bayer Schering Pharma

    Product of United Kingdom. Shipped from United Kingdom

    RxPrescription Required

  2. Buy Bonefos

    Bonefos 800mg

    Manufactured by: Er-Kim Ilac

    Product of Turkey

    RxPrescription Required
    Currently Unavailable.
Generic OptionsWhat is a Generic?

No Generic Alternative.

Please note that the country, manufacturer, and/or shipping country may vary depending on availability. All trademarks and registered trademarks are the property of their respective owners.

General Information On Bonefos

Bonefos is used to inhibit the formation of calcium. It also hinders the dissolution of calcium crystals. Disodium Clodronate is the main ingredient of Bonefos and is an inhibitor of osteoclast-mediated bone resorption. Bonefos is used to treat hypercalcemia and tumor-induced osteolysis. The generic Bonefos drug blocks the cells which are responsible for re-absorbing bones but it does not affect the bone-strengthening cells. No food should be taken an hour before or after taking the medicine. Further, Bonefos 400mg should not be taken with milk.

Side Effects/Precautions For Bonefos

Disodium Clodronate is generally a safe medicine. However, the Bonefos drug may sometime cause mild indigestion or nausea. Some patients also suffer from diarrhea. In case of any discomfort, inform your health care provider. They may adjust your dosage to avoid these side effects. Some rare side effects of generic Bonefos include mild itching and rashes. Sometimes, the drug may also lower the calcium level in blood. Therefore, while on this drug you should go for regular blood checks.

People who have suffered from renal failure should consult their doctor before starting this drug. Also be careful if you take non-steroidal anti-inflammatory medicines. Similarly, those with inflammatory bowel disease should take this medicine under strict medical supervision.

Bonefos Dosage

The recommended daily dosage of Bonefos intake is 1600 mg, taken in one dose or two equally divided doses. The tablets have to be taken with a fluid an hour before or after food. If required, the dosage may be increased up to 3200 mg after evaluation. No dose adjustments are required for the elderly. However, for patients with moderate renal impairment and renal insufficiency, the dosage of Bonefos should be reduced to 800 mg per day. Patients with known history of hypersensitivity to bisphosphonates may also take reduced doses as prescribed by their care givers.

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