Boniva (Ibandronate Sodium) and/or alternatives
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General Information On Boniva
Boniva or Ibandronate is a medication used for increasing bone density and preventing bone loss, thereby reducing the chances of bone fractures. Boniva is recommended to post menopausal women who are more susceptible to osteoporosis. Patients who have been using corticosteroid medications for a long time are also advised to consume Boniva. Boniva belongs to group of drugs known as bisphosphonates. Boniva belongs to the group of drugs known as bisphosphonates that assist your body to suppress osteoclast activity and inhibit bone turnover/resorption. Buy Boniva as it assists patients in increasing and maintaining their bone strength.
Side Effects for Boniva
Use Boniva with caution if you already have low calcium levels, as this medication can cause hypocalcemia. Ask your doctor to prescribe Vitamin D and calcium if you are using Boniva. Contact your physician immediately if you notice a tingling or numbness in your toes or fingers, muscle cramps, or spasms or any other signs of low calcium levels in your blood. You may experience inflammation or irritation in the esophagus, feel some pain in your joints, bones, or muscles, and develop unusual thighbone fractures when using Boniva. Users can also develop severe allergic reactions such as rashes, dizziness, blurred vision, or find it difficult to breathe. If this happens, stop using the medication immediately and contact your healthcare provider when you notice any side effects of Boniva.
Before getting started with Boniva, inform your physician if you are pregnant, planning to conceive, or are breastfeeding. Inform your doctor if you have any problem with your esophagus such as difficulty swallowing or any digestive disorders. If you have a kidney disorder, stomach ulcers, or if your body does not absorb minerals easily, your doctor should be notified in advance before you start using this bisphosphonate before you buy Boniva.
Doctors usually recommend taking a single tablet of Boniva 150 mg every month or can prescribe a daily dose of Boniva 2.5 mg tablets. If you are taking one tablet a month, then take it on the same date every month. If you are using Boniva daily, then take this tablet on an empty stomach first thing in the morning with a tall glass of water. Do not take this medication with milk or any other liquid. You should not eat anything for up to one hour after using Boniva. Swallow the whole tablet and do not crush it or break it to avoid irritation in esophagus. In case of a drug overdose, consult your physician immediately. Your doctors may recommend you Vitamin D and calcium supplements when you buy Boniva.
Inform the doctor about all the prescription, non-prescription and over the counter medications that you are using before they recommend that you take Boniva. Calcium products and multivalent cations like magnesium, aluminum, and iron can slow down Boniva absorption. Therefore, take Boniva on an empty stomach and do not consume any oral medications or food for a minimum of 60 minutes after taking this medicine. Boniva can interact negatively with non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin. The use of Boniva can alter the results of bone-imaging lab tests. Therefore, inform your radiologist in advance if you are on Boniva.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.