Bystolic (Nebivolol Hydrochloride) and/or alternatives
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General Information On Bystolic
Your doctor may recommend you to buy Bystolic (generic name: Nebivolol) if you are suffering from high blood pressure. Nebivolol belongs to the category of beta-blockers, and by lowering high blood pressure in patients, it also helps in preventing other complications like kidney problems, heart attacks, strokes, and decreased libido. Bystolic works by preventing adrenaline from acting on your blood vessels and heart, thus reducing blood pressure, lowering the pulse, and lessening the strain on the patient’s heart. Sometimes, the drug can also be used for treating heart conditions like coronary artery disease and angina. The medicine is available in the form of an oral drug which is to be taken as directed by your doctor.
Side Effects for Bystolic
Tiredness, dizziness, headache, slow heartbeat, nausea, and insomnia are some of the common side effects related to Bystolic. To lower the risks of lightheadedness, you should try to rise from a sitting or sleeping position slowly. As the drug reduces blood flow to your feet and hands, they may become too cold, and for this reason, you need to keep yourself warm. Some serious but rare side effects of the drug may include asthma, sudden weight gain, extreme tiredness, and swelling in the ankles or feet. An allergic reaction to Bystolic can be identified by rashes, hives, itching or swelling of the face, tongue, throat, or lips, breathing trouble, and severe dizziness. If you think you are allergic to the medicine, then you should immediately stop using it and inform your doctor about your symptoms.
Before taking Bystolic, you should inform your doctor if you have anaphylaxis, blood circulation problems like Raynaud’s disease, breathing problems like asthma or COPD, heart problems like irregular heartbeat or heart failure, diabetes, kidney or liver disease, mood disorders like depression, muscle disease like myasthenia gravis, tumors like pheochromocytoma, or hyperthyroidism. If you are to undergo a surgery or dental procedure, you should inform your dentist or doctor that you are on Bystolic treatment. As the drug makes you dizzy, you should not perform any activities that require complete alertness, such as driving a vehicle. You should also limit alcohol intake, as liquor may worsen the condition. If you feel your symptoms have been relieved, you should not stop using the medicine until your doctor tells you to do so. Doing so suddenly can increase your risks of developing chest pain, irregular heartbeat, or heart attack. The Bystolic dose needs to be decreased gradually over a period of 1-2 weeks.
Most patients are advised to start the treatment with Bystolic 5mg per day, with or without other medications. If you are suffering from moderate hepatic impairment or severe renal impairment, you can start the treatment with Bystolic 2.5mg once a day and increase it as needed. Patients being treated exclusively for high blood pressure can increase the dose every 2 weeks up to a maximum of Bystolic 40mg.
Your doctor will not recommend you to buy Bystolic if you are already taking heart rhythm medicines like amiodarone, quinidine, and mexiletine, antidepressants like fluoxetin and paroxetine, beta-blockers like atenolol, labetalol, propranolol, sotalol, and carvedilol, along with digitalis, reserpine, and colinidine.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.