Celontin (Methsuximide) and/or alternatives
No Generic Alternative.
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General Information On Celontin
Celontin (generic name: Methsuximide) is used by itself or along with other medications to control and prevent petit mal or absence type of seizures. Methsuximide belongs to the category of anticonvulsants, which work by gaining control over abnormal electrical activities in the patient’s brain during seizures. This medicine is available in the form of an oral capsule, which is to be taken as prescribed by your doctor.
Side Effects for Celontin
Dizziness, drowsiness, loss of appetite, stomach or abdominal pain, vomiting, nausea, diarrhea, weight loss, headache, and lack of coordination are some common side effects of the drug. Some patients taking Celontin may also complain of suicidal thoughts, depression, and mental or mood changes. Contact your doctor immediately if you notice sudden changes in your moods and thoughts and witness behavioral changes like signs of depression. You also need to watch out for swelling or pain in the joints, rashes on the cheeks and nose, easy bleeding and bruising, rapid breathing, severe tiredness, and flu-like symptoms such as persistent sore throat and fever. An allergic reaction to Celontin can be identified by itching or swelling of the face, throat, tongue, or lips, breathing trouble, severe dizziness, rashes, or hives.
Before your doctor recommends you to buy Celontin, you should inform him/her if you have an allergy to methsuximide, ethosuximide, or any active or inactive ingredients in the medicine. You should also consult your doctor if you have a severe kidney or liver problems. As Celontin makes you drowsy or dizzy, you should not drive a vehicle, use a machine, or do any such activity that calls for complete alertness. Alcoholic beverages may worsen the side effects of the drug, and so, you should limit your alcohol intake; if possible, avoid alcohol altogether as long as you are on Celontin treatment. If you are pregnant or breastfeeding, you should use Celontin only if it is clearly needed, because its safety during these instances has not been clearly indicated.
During the first week, you will be given Celontin 300mg per day, which can be increased after one week to Celontin 300mg for 3 weeks. The daily dose should not exceed Celontin 1.2g. Smaller children are prescribed one Celontin 150mg capsule per day. The drug can be recommended to you along with other anticonvulsant medicines in order treat your condition efficiently.
As the drug causes dizziness, you should inform your doctor if you are taking other similar drugs including antihistamines, sleeping pills, anti-anxiety medications, muscle relaxants, narcotic pain relievers, and antidepressants. These may include alprazolam, zolpidem, diazepam, cetirizine, codeine or diphenhydramine. Some medicines for cold and cough and allergies may also contain drugs that may cause drowsiness. Apart from these, you should inform your doctor about all the medicinal products you are taking at present, including prescription drugs, over-the-counter medicines, herbal products, health supplements, and topical applications. Depending on your condition and the other drugs you take, your doctor will be able to decide whether Celontin is the right drug for you or not.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.