Climara (Estradiol Hemihydrate) and/or alternatives

General Information On Climara

Climara is used for treating symptoms of menopause in women such as burning, itching and dryness in the vagina and problems with urination. Climara contains estradiol, a female sex hormone that is responsible for regulating several processes in the female body. Climara is available in the form of skin patches that need to be applied inside the vagina so that the symptoms can be relieved. The skin patch works by releasing the drug slowly so that it is absorbed through the patient’s skin. You can also buy Climara to treat ovarian disorders, abnormal vaginal bleeding, infertility, and postmenopausal osteoporosis.

Side Effects for Climara

Headache, dizziness, lightheadedness, bloating, weight changes, nausea, increased or decreased libido, skin redness or irritation at the application site, and breast tenderness are some commonly experienced side effects of Climara. However, you should inform your doctor if you experience mental or mood changes like memory loss or severe depression, changes in vision or loss of vision, swelling of the feet or hands, pelvic, stomach, or abdominal pain, breast lumps, vomiting, unusual vaginal bleeding like breakthrough bleeding, prolonged or recurrent bleeding or spotting, unusual vaginal odors, itching, or discharge, and yellowing of the skin or eyes. Some serious but rare side effects of Climara may include trouble breathing, slurred speech, weakness on one side of body, chest pain, severe headache, or calf swelling or pain.

Precautions

Before taking Climara, you should inform your doctor if you have abnormal and undiagnosed vaginal bleeding, liver disease, history of heart attacks, stroke, or blood clots, or any cancer like breast cancer, particularly non-metastatic cancer. In addition, consult your doctor if you suffer from asthma, diabetes, migraine headaches, seizures, heart disease, hypothyroidism, kidney disease, certain hormonal problems, depression, toxemia, cholestatic jaundice, uterine fibroids, gallbladder disease, porphyria, lupus, or excessive weight gain. If you are to undergo a surgery or are going to be confined to the bed for a long time, you should inform your doctor that you are using Climara skin patches, as you may need to observe certain precautions. Sometimes, Climara can cause patchy darkening of your face, which can be intensified when exposed to the sun. Therefore, you should avoid getting exposed to direct sunlight, and if necessary, wear protective clothes and use sunscreen. You should avoid smoking, as doing so may increase your changes of getting blood clots.

Climara Dosage

You may be advised to use a weekly patch which releases Estradiol 0.075mg, 0.05mg, or 0.1mg per day. After one week, you will need to replace the patch. Before doing that, observe the area where the old patch was applied. If it has become red, irritated, or inflamed, try to apply the new patch on a new site.

Interactions

Before you buy Climara, you should inform your doctor if you are using corticosteroids like prednisone, blood thinners like warfarin, or hydantoins like phenytoin. Also consult him/her if you are using liver enzyme medicines, azole antifungals, macrolide antibiotics, cimetidine, carbamazepine, rifamycin, ritonavir, Phenobarbital, and St. John’s Wort.

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