Coreg CR (Carvedilol CR) and/or alternatives
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General Information On Coreg CR
Coreg CR is a prescription only drug that is used in the treatment of specific heart related ailments. It belongs to the family of drugs known as beta-adrenergic blocking agents, more commonly known as beta blockers. These agents thwart the effects of epinephrine, as a result of which the heart beats slowly and with a lower amount of force ultimately lowering the blood pressure. In addition, it also works on alpha receptors thereby relaxing the peripheral blood vessels. Coreg CR drug is indicated to treat mild to severe heart failure and hypertension. The drug is also approved for use in patients whose patients who are otherwise stable post a heart attack but the left ventricle has not returned to its normal functioning.
Side Effects / Precautions For Coreg CR
The active ingredient of this medication is carvedilol phosphate. Do not take the drug if you have asthma, bronchitis, arrhythmias (problem with the sinus node), slow heart rate, lung problems, thyroid disorders, severe liver disorders, atrioventricular blocks or you have a history of hypersensitivity to carvedilol phosphate or any other component of the medicine. It always makes prudent sense to let your healthcare provider know of all your current medications as well as past medical history before he recommends Coreg CR, whether brand or generic. In addition, your healthcare provider should know if you are pregnant, lactating or you are planning to get pregnant.
Most people respond to the drug quite well, however, some adverse reactions are sometimes observed. For people who have been indicated the drug for high blood pressure, the most common side effect observed is dizziness. If you are taking the drug for left ventricular dysfunction, some potential side effects include tiredness, low blood pressure, dizziness, diarrhea, an increase in weight, a slow heart rate, a general lack of energy and hyperglycemia.
Dosages For Coreg CR
The medicine is available in a capsule form in strengths of 10 mg, 20 mg, 40 mg and 80 mg. Both the brand and generic versions are available in the same strengths. Take the drug exactly as prescribed. Do not change the dosage without the doctor’s consent. The capsules are suggested to be taken with food. Swallow the capsules directly, do not crush or chew them. You should store Coreg CR at temperatures below 30oC.
Why Buy Coreg CR From online prescription service RX World?
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.