Crixivan (Indinavir Sulfate) and/or alternatives

General Information On Crixivan

Patients are prescribed Crixivan (Indinavir) to treat HIV (Human Immunodeficiency Virus) infections. The drug works by preventing the virus cells from multiplying in the body. This drug belongs to a group of medicines called protease inhibitors. It is important to note that though Indinavir helps treat patients with HIV-1 infection, it does not cure the infection completely, nor does it prevent the spread of the virus. HIV-1 protease is an active enzyme that causes the multiplication of the HIV virus. Crixivan helps restrain the level of activity of the protease enzyme thereby blocking the replication of the virus.

You can also learn more about the drug by reading the patient information that comes in the package when you buy Crixivan.

Side Effects for Crixivan

Common side effects of Crixivan include fatigue or asthenia, abdominal pain, fever, nausea, heartburn and vomiting. Some may experience back pain or spot blood in their urine. Darkening of the urine, decrease in the amount of urine passed, pale or yellow skin and eyes, dark or clay colored stools, along with loss of appetite and extreme thirst are also common adverse reactions to this drug.

Other side effects include pain in the chest, jaw and left arm, excessive sweating, shortness of breath, easy bleeding or bruising, rise in the level of blood sugar, and changes in body fat. Serious but rare allergic reactions include rashes, itching, swelling of the face, tongue, throat and mouth, and severe dizziness and breathing problems.

It is important to contact your doctor immediately if you were to experience any of the above side effects. It is equally important to note that the above list is not exhaustive. Thus, you should inform your doctor and get medical help if you experience any discomfort after using this drug, even if it does not belong to the above list.

Precautions

It is important to drink lots of water, at least 1.5 liters every day, when consuming Crixivan.

Secondly, inform your doctor in detail about your medical history, including if you have any allergies to any medicine or ingredient, or a history of liver or kidney disease, including kidney stones, high cholesterol and bleeding disorders. Before you buy Crixivan, make sure your doctor is aware of these medical conditions so that the dosage can be adjusted accordingly, especially where necessary.

This drug may interact adversely with pregnancy and thus, it is important to inform your doctor if you are pregnant or become pregnant before continuing with your dosage. Moreover, it is essential to note that Crixivan affects the baby through breast milk. So, avoid Crixivan if you are breastfeeding.

Crixivan Dosage

The recommended dosage is 2 tablets of Crixivan 400mg, taken every eight hours. It is important to follow the eight hour cycle when using this medication. Moreover, it is important to take Crixivan 400mg without food, but with water. In fact, the dosage should be consumed either one hour before any meal or at least two hours after the meal. Your recommended dose of Crixivan may be lowered if it is taken in combination with other drugs, namely, Delavirdine, Itraconazole, Ketoconazole, and increased when taken with Rifabutin. Crixivan is also available in Crixivan 100mg tablets and Crixivan 200mg tablets.

Interactions

Several drugs interact with Indinavir, namely Amiodarone, Atazanavir, some Benzodiazepines, Ergot alkaloids, St. John's Wort, etc., which adversely react with this drug and should be avoided. It is important to seek the advice of your doctor before using any drug in combination with Crixivan as certain combinations could be life threatening or cause serious interactions.

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