Dantrium (Dantrolene Sodium) and/or alternatives
No Generic Alternative.
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General Information On Dantrium
Dantrium or Dantrolene sodium is a drug used for curing muscle cramps and tightness caused due to nerve disorders such as cerebral palsy, stroke, injury and multiple sclerosis. Dantrium is a muscle relaxant; it eases stiffness and muscle pain and improves your ability to move. Dantrium is used in combination with other medications to treat high fever caused due to surgery or anesthesia. Dantrolene sodium is used for curing uncommon conditions such as neuroleptic malignant syndrome that causes muscle stiffness, palpitations and high fever.
Side Effects for Dantrium
Dantrium users can experience weakness, dizziness, drowsiness, fatigue, nausea and diarrhea during the initial days when the body is trying to adjust to this drug. You can also experience constipation, headache and slurred speech. The problem should dissipate after few days, but contact your doctor if the problem persists. In rare cases, patients using Dantrium may experience severe side effects like sun sensitivity, dark stools and vomiting, violent mood swings, change in vision, problems swallowing, difficulty urinating, severe constipation, palpitations, seizures and rapid heartbeat. Contact your doctor immediately if you notice the above side effects or experience signs of infection, swelling of the feet/ankles, and breathing problems.
Make your doctor aware of all the medications that you are using, and are allergic to, before you start using Dantrolene. Inform the doctor if you are suffering from disorders such as hepatitis, cirrhosis or suffer from breathing/heart problems like chronic obstructive pulmonary disease. Using Dantrium can make you extremely sensitive to the sun. Therefore, use adequate protection when you move outdoors and avoid sunbathing or visiting tanning booths. Dantrium is not recommended for pregnant women and mothers who are breastfeeding. Dantrium usage can make you dizzy and drowsy. Do not undertake any activity that requires high alertness after using this muscle relaxant.
Dantrium 25mg, Dantrium 50mg and Dantrium 100mg capsules are available in the market. Doctors may initially start with a small dosage and gradually increase the dose until the right strength for you is found. Therefore, you may buy Dantrium 25mg for 7 -14 days then the dose will be increased to Dantrium 50mg for the next 7 days. If you still do not find relief, then doctors may recommend you to buy Dantrium 100mg. Manufacturers suggest that your daily dose for Dantrium should not exceed 400mg. The right dosage depends on the age and weight of the patient, medical history and your response to the tablet. If you are using Dantrium for curing hyperthermia then the treatment will continue for several weeks.
Inform doctors about all the prescription/non-prescription/herbal/ and vitamin supplements that you are using before you buy Dantrium. Medications containing estrogen can interact negatively with Dantrium. As this drug can make you sleepy, the drowsiness can increase if you are already using medications like antihistamines, sedatives, anti-anxiety medication, anti seizure medications, muscle relaxants, psychiatric medication and other muscle relaxants. Tell your doctor if you are using hormonal medications or birth control pills as well as heart or blood pressure medications before they prescribe Dantrium.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.