Diamox Sequels (Acetazolamide ER) and/or alternatives
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General Information On Diamox Sequels
A carbonic anhydrase inhibitor, Diamox Sequels is used for the treatment of glaucoma. This medicine works by slowing the activity of carbonic anhydrase, a protein found in red blood cells. In addition to glaucoma, this medicine is also used to treat, as well as prevent AMS (acute mountain sickness). The generic name of this drug is Acetazolamide.
Side Effects for Diamox Sequels
Like other drugs, this medicine may cause certain side effects. Common and less serious side effects of this medicine include: mild nausea, vomiting, headache, drowsiness, or dizziness, constipation, diarrhea, metallic taste in your mouth, mental/mood changes (such as irritation, confusion, or nervousness), tinnitus (a condition characterized by ringing in the ears), or increased sensitivity to sunlight. Generally, the above symptoms appear only at the start of the treatment. Once the patient’s body gets used to Diamox Sequels, the aforementioned symptoms subside and eventually dissipate on their own. Continue to use the drug as prescribed by your doctor even with the advent of one or more of the above side effects. Also, contact your doctor in case the aforementioned symptoms continue to occur even after a few days or if the side effects become a cause for concern.
Less common but serious side effects of Diamox Sequels include: sore throat, fever, chills, unusual bruising or bleeding, joint pain, pain in your lower back, or tingling/numbness in your fingers or toes. You must contact your doctor immediately if you notice any of the aforementioned symptoms.
This drug is unlikely to trigger a serious allergic reaction. With that said, you must immediately stop taking this medication and call your doctor if you experience: hives, swelling of your body parts (especially your face, lips, or tongue), or breathing difficulties.
The above list does not cover all the side effects of Diamox Sequels. To know more about this subject, read the patient information leaflet that you receive when you buy Diamox Sequels. This small booklet contains useful information such as the complete list of side effects, precautions, and other necessary information.
You should not buy Diamox Sequels if you are allergic to Sulphonamides, Sulphonamide derivatives such as Acetazolamide, or other ingredients that are present in this medicine. Make it a point to tell your doctor your medical history, especially if you have diabetes, adrenal gland problems, liver or kidney disease, cardiovascular disease, low levels of potassium or sodium, lung disease, or hormonal disease.
Pregnant and breastfeeding women should use this medicine only if their doctor advises them to do so. Avoid driving and other activities that require you to stay alert if this medicine causes drowsiness, dizziness, or vision problems such as short-sightedness.
Diamox Sequels Dosage
The recommended dosage is Diamox Sequels 500mg twice a day. It is absolutely critical that you take this medicine as directed by your doctor. You should store this medicine at room temperature away from heat and moisture.
Certain drugs such as aspirin, salicylates, salsalate, and diflunisal may decrease the efficacy of Acetazolamide or increase some of its side effects. In addition to these few, many other drugs may also interact with Diamox Sequels. Before starting treatment, inform your doctor about all the medicines that you are using, including herbal supplements.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.