Effient (Prasugrel Hydrochloride) and/or alternatives
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General Information On Effient
Effient (prasugrel) is a drug that is used to prevent blood clotting. The drug prevents coagulating or clotting of platelets in the blood that may occur when a patient suffers from a blood vessel or heart related disease. Typically, doctors prescribe Effient to patients suffering from acute coronary syndrome and ailments related to blood vessels. The drug is also prescribed to patients who have suffered from heart attack or stroke
Side Effects for Effient
Although Effient is effective in preventing blood clotting, some patients may experience a few side effects, mostly due to their medical condition. Some of the most common side effects associated with the consumption of Effient are: Unusual bleeding in the gums or nose bleeding; fatigue and dizziness, jaundice, bleeding while urinating, bleeding while excreting, tarry or black stools, sudden mild fever, appearance of red or purple spots under the skin, chest pain or nauseous feeling, heavy perspiration, swelling in tongue, throat or lips, coughing and vomiting.
Some patients may feel numb on one side of the body, their vision may become blurry, or they may experience difficulty while speaking. Some women on this drug may also experience sudden vaginal bleeding.
If you experience any of the above mentioned side effects due to the consumption of Effient, you must immediately consult your doctor and discuss the problem.
Doctors worldwide strictly recommend patients to stay away from taking Effient tablets if they are allergic to Parasugrel. It is important that before you start Effient, you inform your doctor if you have any internal bleeding problems in your intestines or stomach. Also, if you feel pain while excreting or have bloody or black stools, you must immediately bring this to your doctor’s attention before continuing with Effient. You must also not consume non-steroidal anti-inflammatory drugs (NSAIDs) such as Ibuprofen, Piroxicam, Ketoprofen during the course of Effient medication without your doctor’s advice.
If you are suffering from any dental problems or are required to undergo any dental surgery, you must bring this to your doctor’s notice well in advance if you are taking Effient. This is important because the dentist would ask you to stop using Effient 7 days before to prevent excessive bleeding. If you are a lactating women, you must not use Effient without your doctor’s advice.
Doctors determine Effient dosage depending on the patient’s health condition and their weight. Typically, the first dosage of the drug is higher than the subsequent dosages. Ideally, doctors recommend Effient 60 mg as the first dosage. After the first dosage, the standard amount is 10 mg once a day.
Effient has the potential to interact with other medications that contain hydrochloride. Thus, it is important that you tell your doctor about other medication that you are taking before the doctor recommends Effient. Ignoring this can lead to bad side effects with serious consequences that can even be fatal. Consult your doctor about all medications you are taking before you buy Effient
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.