Emend (Aprepitant) and/or alternatives
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General Information On Emend
Emend is prescribed for prevention of acute and delayed nausea and vomiting induced by chemotherapy and for the prevention of postoperative nausea and vomiting. It may also be used to treat cyclic vomiting syndrome. It is an antiemetic chemical compound and works by blocking the neurokinin 1 receptor.
Side Effects/Precautions for Emend
Emend (Aprepitant) may produce side effects like weakness, tiredness, dizziness, heartburn, loss of appetite, headache, itching, fever, stomach pain, constipation, hair loss and gas. It may also produce serious side effects like hives and rashes and if you experience any of them, call your doctor at once. Let your doctor know if you are allergic to brand or generic Emend. The drug Emend should be avoided if you are taking Hismanal, Cisapride, Terfenadine and Pimozide. If you are taking any other prescribed or over the counter medication, herbal products or nutritional supplements, let your doctor know about it, so that he can monitor the side effects and reactions carefully.
Aprepitant can affect a fetus, so inform your doctor if you are pregnant or if you plan to get pregnant during the course of the treatment. Do not breastfeed while taking brand or generic Emend. If you are taking birth control pills, inform your doctor about it and also let him know if you have had any liver disease. You can continue with your normal diet unless advised otherwise. The medication must be stored in a tightly closed container, away from the reach of children and from excess heat and moisture. In case you overdose on the Emend drug and experience symptoms like drowsiness and headache then call your doctor immediately.
Emend is available in 40 mg, 80 mg and 125 mg capsules. When used for preventing chemotherapy induced nausea and vomiting, this drug is given as part of a regimen for a period of three days. The recommended dosage of Emend is 125 mg, taken orally one hour prior to the chemotherapy on Day 1 and followed by 80 mg in the morning daily on Day 2 and Day 3. When used for prevention of post operative nausea and vomiting, the recommended dosage is 40 mg orally, within 3 hours prior to induction of anesthesia. No dosage adjustment is required for patients with renal impairment and mild to moderate hepatic impairment.
Why Buy Emend From Pharmacy RX World?
You can buy Emend in 80mg and 125mg dosages as prescribed by your physician. Pharmacy RX World offers you quick delivery within seven to ten working days on all orders placed online.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.