Enablex (Darifenacin Hydrobromide) and/or alternatives
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General Information on Enablex
Enablex is an extended-release medicine. It is used for the treatment of an overactive bladder (urgent or frequent urination) and urine leakage (incontinence). Enablex does this by reducing muscle spasm of the urinary tract and the bladder. The recommended starting dosage of generic Enablex is 7.5 mg daily. This may be increased to Enablex 15mg based on your response to the medicine. This tablet should be consumed once daily with some liquid (preferably a full glass of water).
Side Effects / Precautions for Enablex
When using the Enablex drug you may experience side effects like constipation, dry mouth, abdominal pain or indigestion. Since this drug belongs to the category of medicines known as anticholinergics, you may even experience blurred vision and heat prostration (this can occur if Darifenacin is taken in a hot environment). It is advisable to be over cautious while driving or while doing any other dangerous activity if you are taking this drug.
You should avoid taking generic Enablex or Darifenacin if you are allergic to it or any of its ingredients. Other conditions in which Enablex should not be taken are if you have trouble emptying your bladder (known as urinary retention), if you have slow or delayed emptying of stomach (known as gastric retention) or if you have uncontrolled narrow-angle glaucoma (eye problem).
You should consult your doctor before taking the drug if you are pregnant. Enablex, during pregnancy, should only be taken if its benefits outweigh the risks to the foetus. There is no proof of whether Enablex affects breast milk. Therefore, doctors are normally cautious before administrating Enablex to a nursing mother.
The starting dose of Enablex is 7.5 mg administered daily once. The dose of the extended-release tablet is adjusted based on an individual patient’s response. If the dose adjustment is required then it may be increased to a maximum of 15 mg, administered daily once. The dose increment may be done even within 2 weeks after beginning the treatment. In patients with hepatic impairment which is mild to moderate in nature, the maximum dose of Enablex is 7.5 mg and should not be exceeded. Patients with severe hepatic diseases must avoid the drug. The drug should be swallowed completely with any liquid and may be administered with food or without food.
Why Buy Enablex From Pharmacy RX World?
You can buy Enablex from us as we are dedicated to providing outstanding service, quality medicines and a free refill reminder service. Further, we can guarantee the lowest prices of this drug in the market.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.