Evista (Raloxifene Hydrochloride) and/or alternatives
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General Information On Evista
Evista or raloxifene hydrochloride is a drug used for treating and preventing osteoporosis in women after they reach menopause. Evista works by preventing bone loss that helps in maintaining strong bones and reduces the chances of fractures. Using raloxifene hyrdrochloride also prevents invasive breast cancer that commonly affects menopausal women.
Evista is not a hormonal medicine and does not help postmenopausal women in raising their estrogen and progesterone levels. However, you should buy Evista, if recommended by your doctor, as it acts as a selective estrogen receptor modulator (SERM) and works on certain parts of the body like estrogen hormone. Using Evista helps in maintaining good bone health but it does not relieve menopause symptoms like hot flashes, night sweats etc. Evista is ineffective in preventing heart ailments in postmenopausal women. You should only buy Evista if you have reached menopause. Children and younger women should not buy Evista.
Side Effects for Evista
Hot flashes, night sweats, headache, spinning sensation, leg/joint pain, excessive sweating, nausea, stomachache, and a stuffy and runny nose are some of the common side effects Evista users will notice during the initial days of using this drug. The problem should subside within a week, but if the problem persists, stop using Evista and contact your physician. In rare cases, you many notice sudden weakness or numbness in one side of your body, blurring of vision or slurred speech, swelling and pain in legs, chest pain, breathing problem, unusual bleeding, tenderness or pain in the breast, burning sensation during urination and severe backache. Raloxifene can sometimes cause serious blood clot formation in the eyes, lungs and legs. If you notice any of the above symptoms, contact your healthcare provider right away.
Before you buy Evista, inform your doctor if you are pregnant, breastfeeding or you have suffered from blood clots (pulmonary embolism, deep venous thrombosis, retinal vein thrombosis). In addition, tell your physician if you are taking blood pressure medication, have heart ailments, coronary artery disease, kidney disease, liver disorder, a medical history of stroke, high triglyceride levels, have suffered from breast cancer and have still not reached menopause phase.
Doctors recommend Evista 60mg tablets to be taken once a day with/without food. You can take Evista 60mg anytime during the day, but you should try taking this medication every day at the same time. Take this medicine with a tall glass of water. If you are undergoing any surgery, then stop taking this medication 3 days in advance. Evista 60mg is only a part of a treatment and doctors may recommend you to take Vitamin D and calcium supplements along with following a good diet and exercise regime. Follow the routine as per doctor’s recommendation to see the best results.
Inform doctors about all the prescription/non-prescription/herbal/vitamin supplements that you are using before you buy Evista. When you start with Evista, inform the doctor if you are using medicines like cholestyramine, warfarin, or other blood thinners, diaoxide, diazepam, or using birth control pills. You should not take this medication if you are undergoing hormone replacement therapy for treating menopause symptoms or using any other medication to raise estrogen/progesterone levels.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.