Fareston (Toremifene Citrate) and/or alternatives
No Generic Alternative.
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General Information On Fareston
Fareston is a medication that slows down the growth of metastatic breast cancer. It does this by blocking the estrogen from reaching the cancer cells. Certain cancer cells require estrogen to grow. However, taking Fareston does not actually kill existing cancer cells.
Side Effects for Fareston
Serious side effects of Fareston are rare, and they include severe dizziness, nausea, easy bruising, vaginal bleeding, sudden numbness, chest pain, blurred vision, and tremors. Other side effects that may be seen are dizziness, vomiting, loss of appetite, and pain spreading to the arm or shoulder. It also includes red or purple spots under the skin, sudden cough, wheezing, rapid breathing, and coughing up of blood. Fareston may also have a serious side effect of loss of movement in some part of the body. Stop your medication and seek immediate medical help if you face any of these side effects.
Some milder side effects of taking Fareston may include mild nausea, constipation, sweating, itching, and hot flashes. It may also include depression, hair loss, vertigo, and swelling of the hands or feet.
If you buy Fareston, it may increase the risk of developing a condition called endometrial hyperplasia, which may result in a cancer of the uterus. Before you buy Fareston, talk to your doctor, and assess your risks. If you suffer the symptoms of a serious heart rhythm disorder, you must stop medications and consult your doctor at once. These symptoms may include severe dizziness, fast or pounding heartbeat, and fainting. Inform your doctor beforehand if you are allergic to Toremifene, which is the generic name of Fareston. Tell your doctor if you have a history of Long QT syndrome or low levels of potassium and magnesium in the blood. Let your doctor know if you have endometrial hyperplasia, bone cancer, or if you have ever had a blood clot. Avoid grapefruits or grapefruit juice when you are on Fareston medication. Grapefruit products may interfere with Fareston. Ask your doctor to discuss what kinds of grapefruit products need to be avoided.
Fareston is usually administered as a Fareston 60mg oral tablet, prescribed once daily. The prescription may also vary according to each individual patient’s condition. Take the medication exactly as ordered by the doctor. Fareston 60mg can be taken with or without food. It is recommended that this medication be taken at the same time of the day every day. Visit your doctor regularly for diagnostic tests to see if the medication is not causing any side effects. An overdose of Fareston 60mg can result in severe side effects that were mentioned above. If this is observed in a Fareston patient, they would require immediate medical assistance. You may only buy Fareston if it is prescribed to you by your physician.
Inform your doctor about every other medicine you consume or are prescribed, especially Trisenox, Isoniazid, St.John’s wort, Prograf, Warfarin, and vitamin or minerals supplements that contain vitamin D or calcium. You must inform your doctor if you are taking antibiotics like Biaxin, Erythromycin, Levofloxacin, Ofloxacin, Rifabutin, Rifampin, or Tellithromycin. Tell your doctor if you are taking antidepressants, antifungal medications, or seizure medications before you buy Fareston.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.