Janumet (Sitagliptin Phosphate/Metformin Hydrochloride) and/or alternatives
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General Information On Janumet
Janumet (Metformin and Sitagliptin) is an oral diabetes medication. It is used to control blood sugar levels. Metformin helps in decreasing the production of glucose (sugar) in the liver and also helps in decreasing the absorption of glucose by the intestines. Sitagliptin helps in regulating insulin levels which your body produces after eating. The Janumet drug can be used for type 2 diabetes patients who do not use insulin injections on a daily basis. This medicine should be used along with a strict exercise and diet regimen. You should remember that Janumet is not used for the treatment of type 1 diabetes. It comes in the form of tablets and can be taken in 50mg Sitagliptin/500 mg Metformin strength initially which can be increased to 50 mg Sitagliptin/1,000 mg Metformin after consulting with your doctor.
Side Effects / Precautions for Janumet
Janumet should not be used for the treatment of Ketoacidosis. Further, you should refrain from using this drug if you have had pancreatitis (inflammation of the pancreas) in the past. Common side effects of generic Janumet are diarrhoea, vomiting, nausea, gas, upset stomach, indigestion, weakness, headache, upper respiratory infection, sore throat and a stuffy or runny nose. If you are on this medication you may also experience swelling in the hands or legs. This can generally happen if you are taking Janumet along with Rosiglitazone (Avandia).
The FDA has categorised generic Janumet as category B drug for pregnancy. It is not expected to be harmful for the unborn child, however, you should tell your doctor about your pregnancy if you are taking this medicine.
Janumet Dosage
The standard doses for Janumet therapy is 50 mg of Sitagliptin/500 mg of Metformin Hydrochloride daily twice for patients whose illness is not controlled by exercise and diet alone. Also, a recommended dose of 50 mg Sitagliptin/1000 mg of Metformin hydrochloride is administered daily twice for patients who do not show adequate glycemic control. The dosage for anti-hyperglycemic treatment is determined on the basis of the patient’s current treatment regimen. For patients on monotherapy of Metformin the starting dose of Janumet must provide Sitagliptin at 50 mg daily twice. For patients on monotherapy of Sitagliptin the starting dose is 50 mg Sitagliptin/500 mg Metformin Hydrochloride daily twice.
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