Neupro (Rotigotine) and/or alternatives
No Generic Alternative.
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General Information On Neupro
Neupro or Rotigotine is a prescription transdermal patch used to treat Parkinson’s disease symptoms in adults. Neupro can be effective in controlling the disease in its early stages, but it needs to be combined with Levodopa if it is unable to control the disease on its own. You can also buy Neupro for treating Restless legs syndrome, in which the patient feels odd or painful sensations in the body and has an uncontrollable urge to move the legs, usually at night.
Side Effects for Neupro
Some of the common side effects associated with Neupro are vomiting, sleepiness, dizziness, nausea, headache and redness, and irritation and itching on the site of application. Some patients who are using Neupro for treating Restless legs syndrome may experience asthenic conditions like weakness, feeling unwell, and tiredness and headache. You may experience an increase in your sexual desire and may have abnormal dreams as well. You may also experience pruritus, irritability, fatigue, hypertension, and impulse control disorder, such as an uncontrollable urge to gamble. Other side effects that you may experience are an erythematous rash, urinary tract infection, abnormal vision, sinusitis, hallucinations, and respiratory problems.
As somnolence or sleepiness is a side effect of Neupro, you should not drive a vehicle or operate any machinery, as doing so may result in a serious accident. As the back layer of the patch contains aluminum, it needs to be removed if you are going for an MRI or any other medical exam. Before you buy Neupro, you must tell your physician if you have asthma, heart disease, congestive heart failure, high blood pressure, a history of seizures, epilepsy, tremors, or uncontrollable muscle movements. Neupro can be harmful for an unborn baby, and therefore, it should not be used during pregnancy. Rotigotine may also pass in your breast milk and may harm a newborn baby, and so, you should not use it if you are breastfeeding a child. As Neupro may make your dizzy and sleepy, you should not drink alcohol, as it may worsen the side effects.
You can buy Neupro patches in 2, 4, and 6 mg strengths. Initially, you have to apply Neupro 2mg patch for 24 hours, and based on your response and tolerability to the treatment, you can continue using it for a week. After that, you can increase it to Neupro 4mg per day and then Neupro 6mg per day. If you need to discontinue using the patches, then do that gradually by decreasing the strength from 6 to 4 to 2 mg.
Rotigotine is a dopamine agonist, and therefore, it may interact with other dopamine antagonists like neuroleptics and Metoclopramide. You should also not take Neupro with other CNS depressants or sedatives like anti-depressants, antipsychotics, and benzodiazepines. It is advisable to inform your doctor about all the herbal products and medicinal drugs you are taking at present so that he/she can evaluate the interactions between the two and tell you whether to use them or not. You should also inform your doctor if you are planning to start any other medicines during the course of Neupro or if you plan to discontinue using the patch.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.