Omnipaque (Iohexol) and/or alternatives
No Generic Alternative.
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General Information On Omnipaque
Omnipaque is a contrast agent used in medical imaging and is administrated intrathecally in adults for cervical, thoracic, lumbar, or total columnar myelography or for computerized tomography including cisternography and ventriculography. It is also used in arteriography, arthography, nephroangiography, and radiography procedures. The generic name of the drug is iohexol, and when it is administered in the subarachnoid space through the intrathecal route, it gets diffused in the cerebrospinal fluid, thus providing a visualization of the head, spinal cord, and other vessels. Omnipaque is to be administered intravenously through an injection, and this must be done only by a healthcare professional.
Side Effects for Omnipaque
Some of the commonly reported side effects of Omnipaque include backache, headache, stiffness, neck ache, vomiting, and nausea. Most of these reactions occur within 1-10 hours of giving the shot and get better within a few hours. Sometimes, a headache may persist for a few days, accompanied by vomiting and nausea, especially if the patient was not properly hydrated. Some patients may also complain about dizziness, heaviness, hypertonia, hypotension, sweating, loss of appetite, vertigo, photophobia, neuralgia, tinnitus, paresthesia, neurological changes, or difficulty urinating. An allergic reaction to Omnipaque may be identified by hives, rashes, difficulty breathing, severe dizziness, or swelling or itching of the face, throat, tongue or lips. If you experience any of these symptoms, you should seek immediately contact your doctor and tell him/her about the side effects you are experiencing.
You should not buy Omnipaque if you are hypersensitive to the drug. It should also not be given if a significant systemic or local infection is present in the patient, which can lead to bacteremia. Omnipaque should not be given to pregnant women through the intrauterine route, as it may damage the fetus. Administering the medicine to breastfeeding mothers may also result in acute pelvic inflammation or infection in the genital tract. Before taking the shot, you should inform your doctor if you have a history of thyroid problems. If Omnipaque has caused dizziness in your case, you should avoid operating a machine, driving a vehicle, or doing any such activity that requires complete alertness. You should also avoid alcohol within 24 hours of taking the injection, as it may worsen the side effects.
There are three strengths of Ominpaque available, Omnipaque 180, Omnipaque 240 and Omnipaque 300. These contain Iohexol 180mg/ml, 240mg/ml and 300mg/ml respectively. Depending on the type of imaging procedure you require and the degree of contrast needed your physician will determine the correct dosage of Omnipaque for you.
Omnipaque should not be given intrathecally along with any corticosteroid like prednisone, fluocortolone, or betamethasone. You should inform your doctor about all the prescription drugs, non-prescription medications, herbal products, and health supplements you are taking at present. Depending on this information, the doctor will be able to decide whether Omnipaque is suitable for you or not.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.