Ospolot (Sulthiame) and/or alternatives
No Generic Alternative.
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General Information On Ospolot
Ospolot is used for treating focal epilepsy in adults and Rolando epilepsy and psedo-lennox syndrome in children. Generic name of the drug is Sulthiame and it is effective in the treatment of Jacksonian seizures, myoclonic seizures, partial seizures, behavioral disorders, and grand mal seizures related to epilepsy. This drug belongs to a category of drugs known as anti-convulsion agents, which work by inhibiting carboanhydrase enzymes of the nerve cells. This, in turn, reduces and interrupts conduction of stimulus leading to seizure attacks. You can buy Ospolot in form of oral tablets in Ospolot 50mg and Ospolot 200mg strengths.
Side Effects for Ospolot
Gastric complaints may occur in a few patients who use Ospolot. Some other side effects associated with this drug include paresthesias in face or extremities, hyperpnea, tachypnea, dyspnea, headache, dizziness, stenocardia, weight loss, loss of appetite, singultus, double vision and tachycardia. Sometimes, this drug may also lead to joint pain, lack of sex drive, myasthenic phenomena, hallucinations, grand mal state, anxiety and increased seizure activities. Consult your doctor if you notice any of these symptoms.
You should also contact your doctor if you experience weakness in the limbs, slurred speech, hypersalivation and drowsiness leading to coma. An allergic reaction to Ospolot may be identified by hives or rashes all over the body, swelling on tongue, lips, throat or face, trouble breathing or severe dizziness. If you develop any of these symptoms, immediately stop using the medicine and seek medical help.
This medication may cause side effects that are not listed above. You can find the complete list of side effects in the patient information leaflet that is provided to you when you buy Ospolot.
Patients having acute porphyria, hypertension or hyperfunction of thyroid should take Ospolot. Inform your doctor if you have a personal or family history of psychiatric disease or renal insufficiency. You should also tell your doctor if you are allergic to Sulthiame, any other sulphonamide, or any constituents in the drug. While taking Ospolot, your doctor will prefer to monitor your renal function and blood count. Therefore, you should not miss any of your scheduled appointments. If you develop progressive leucopenias or thrombopenias (symptoms are sore throat or fever), your doctor may decide to discontinue the treatment. If you are pregnant or breast feeding, you should take this medicine only if clearly needed, because its safety in these conditions is not established.
Usually, you will be advised to take Ospolot 5mg/kg or Ospolot 10mg/kg. For example, a patient weighing 50kg is likely to be administered a daily dosage of Ospolot 250mg or Ospolot 500mg. However, adjustments can be made depending on the frequency, intensity and type of seizure attacks.
You should not use Ospolot with any other medication that causes dizziness such as sedatives, sleeping pills, tranquilizers, narcotic pain relievers, anti-depressants, anti-seizure medications and muscle relaxants. In addition to the above, inform your doctor if you are taking any other medicinal products, including prescription, non-prescription medicines, or herbal medicines, and health supplements. Your doctor is likely to take this information into consideration while deciding if Ospolot is right medicine for you.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.