Promacta (Eltrombopag Olamine) and/or alternatives

General Information On Promacta

Promacta is used for preventing bleeding episodes in patients suffering from chronic immune thrombocytopenis purpura or ITP, a condition that occurs due to low platelet count in the blood. Generic name of this drug is Eltrombopag Olamine. You can buy Promacta in form of oral tablets. It works by inducing proliferation and differentiation of megakaryocytes in progenitor cells in the bone marrow. This, in turn, increases the production of platelets in the patient’s body. You must know that Promacta does not cure thrombocytopenia; it is used only to treat the symptoms of this disease.

Side Effects for Promacta

Some common side effects for Promacta include mild nausea, upset stomach, vomiting, muscle pain, tingly feeling or numbness, heavy vaginal bleeding, and redness in the eyes. Most of these symptoms are manageable and get better on their own within a few days. In case any of these symptoms worsen or persist, you should immediately contact your doctor.

You should consult your doctor if you experience any of the following serious side effects during the therapy – severe and persistent nausea, dark urine, pain in upper stomach, clay-colored stools, jaundice, sudden weakness or numbness on single side of the body, sudden headache, problems with speech, vision, or balance, chest pain, coughing up blood, rapid breathing, wheezing, sudden cough, warmth, redness, swelling or pain in the legs, unusual bleeding from the vagina, rectum, nose, or mouth, red or purple pinpoints under the skin, and halos around lights.

An allergic reaction to this drug can be identified by hives, rashes, difficulty breathing, severe dizziness, or swelling/itching on the face, tongue, throat or lips. At the appearance of these symptoms, you should discontinue the medication and seek immediate medical help.

Precautions

To ensure this medication is safe for you, inform your doctor beforehand if you are suffering from a liver or kidney disease, blood clotting or bleeding disorder, or blood cancer or bone marrow disorder. You should also inform your doctor if you have high platelet level in your blood, if you have had your spleen removed, or if you have a history of blood clot or cataracts. You should not buy Promacta if you are pregnant or nursing, as it can harm an unborn baby and breastfeeding infant.

Promacta Dosage

At the start of the treatment, you are likely to be advised to take Promacta 50mg once a day. Patients of East-Asian descent, like Japanese, Taiwanese, Korean or Chinese, should be administered Promacta 25mg once a day during the start of their treatment. Do not exceed the maximum dosage of this medicine, which is Promacta 75mg per day.

Interactions

Promacta can affect the working of birth control pills. If you are using them, inform your doctor at the start of the treatment. Try to use a barrier form of contraception to prevent unwanted pregnancy during the treatment. You should also inform your doctor if you are using antibiotics (such as ciprofloxacin or lomefloxacin), oral diabetes medicines (such as nateglinide and rosiglitazone), cholesterol lowering medicines (such as atorvastatin and rosuvastatin), heart rhythm medicines (such as amiodarone and verapamil), narcotic pain relievers (such as hydrocodone and oxycodone), NSAIDs (such as indomethacin and naproxen), or stomach acid medicines (such as cimetidine and famotidine). In addition to the above, other medicines that may interact with Promacta include acyclovir, acetaminophen, fluvoxamine, atazanavir, penicillin G, rifampin, ticlopidine, zileuton, trimethoprim, and methotrexate. It is important to inform your physician about all medications that you are taking.

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