Vesanoid (Tretinoin) and/or alternatives
No Generic Alternative.
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General Information On Vesanoid
Vesanoid is used to treat acute promyelocytic leukemia, a cancer of the blood and bone marrow. The generic name of this drug is Tretinoin, and it works by causing an increase in the growth of normal cells in the blood and bone marrow.
You can buy Vesanoid in form of an oral tablet. The drug is available in Vesanoid 10 mg strength. Tretinoin is the active ingredient in the formulation, which also contains the following inactive ingredients: beeswax, edetate disodium, butylated hydroxyaisole, hydrogenated vegetable oil, soybean oil, and hydrogenated soybean oil flakes.
Side Effects for Vesanoid
You may experience any of the following mild side effects after taking Vesanoid: bone pain, rash or itching, increased sweating, white patches on the lips or inside the mouth, nausea, vomitting, fever, vision problems, headache, or fatigue.
Some patients who buy Vesanoid have reported experiencing the following serious side effects after taking the drug: weight gain, breathing problems, swelling of the feet or hands, bloody, black, or tarry stools, or slurred speech. You should consult your doctor immediately if you experience any of the above side effects.
In rare cases, this drug may trigger an allergic reaction. You must seek immediate medical help if you experience any of the following symptoms after taking Vesanoid: hives, wheezing, trouble breathing, or swelling of the face, lips, or throat.
This is not the complete list of side effects for Vesanoid. To know all the possible side effects of this drug, read the patient information leaflet that you receive when you buy Vesanoid.
You should not take Vesanoid if you are hypersensitive to any of the ingredients present in it. Before you start treatment, inform your doctor about your medical history, especially if you have high cholesterol.
Vesanoid is contraindicated in pregnancy as it can cause premature birth, birth defects, miscarriage, or death of a newborn. Do not buy Vesanoid if you are pregnant. If you become pregnant while treatment is going on, tell your doctor at once. The safety of this drug in breastfeeding women is unknown. Consult your doctor before using Tretinoin if you are breastfeeding.
You should not take Vitamin A supplements while you are taking Tretinoin. This drug may cause vision problems or impair your thinking. Do not drive or perform such activities unless you are sure how you react to Vesanoid.
The recommended dosage is Vesanoid 45 mg/m2 per day for 90 days. You should take your dose with a glass of water (8 ounces).
Certain drugs, when taken with Vesanoid, may decrease its effectiveness or increase some of its side effects. These include: amiodarone, diltiazem, verapamil, mibefradil, fluoxetine, fluvoxamine, cyclosporine, cimetidine, erythromycin, clarithromycin, ketoconazole, itraconazole, HIV medicines (such as saquinavir, ritonavir, nelfinavir, or indinavir), and certain antibiotics (such as demeclocycline, minocycline, or doxycycline).
Other drugs, which are not present in the above list, may also interact with Vesanoid. That is why it is imperative that you inform your doctor about all the medicines that you are currently taking, including herbal and over-the-counter medicines. In addition, while you are taking Vesanoid, do not start any new medication without first consulting your doctor.
IMPORTANT DISCLAIMER: All medical content is supplied by a third party company who is independent from this web site. As such, this web site can not guarantee the reliability, accuracy, and /or medical efficacy of the information provided. In all circumstances, you should seek the advice of a health professional pertaining to drug, treatment and/or medical condition advice. Note that not all products are shipped by our contracted Canadian pharmacy. This website contracts with dispensaries around the world that ship products directly to our customers. Some of the jurisdiction include but are not limited to United Kingdom, Europe, Turkey, India, Canada, Vanuatu, Mauritius, and USA. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others. Please note that the product appearance may vary from actual product received depending on availability.
What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.