Vimovo (Naproxen/Esomeprazole Magnesium) and/or alternatives
No Generic Alternative.
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General Information On Vimovo
Vimovo is used to treat signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is a combination of two drugs, Esomeprazole and Naproxen. Both drugs work differently- Naproxen is a non-steroidal anti-inflammatory medication, which works to reduce the production of chemicals that cause pain, inflammation, and fever. Esomeprazole is a proton pump inhibitor, which works to reduce the production of gastric acid in the intestines and the stomach. This curbs the onset of gastric ulcers in those using NSAIDs. The drug may cause side effects, so it is necessary to consult your doctor before you buy Vimovo.
Side Effects for Vimovo
Some people may experience certain side effects after taking Vimovo, such as indigestion, diarrhea, or abdominal pain. The drug may also cause stomach ulcers or inflammation of the lining of the stomach. Some people may also experience severe side effects such as symptoms of low magnesium in the blood, irregular heartbeat, difficulty in swallowing, breathing problems, hands and feet swelling, unexplained weight gain, cough, and fever. You may become more susceptible to bruising, bleeding, and fainting. You may also notice a change in the amount of urine passed. This is not a complete list of side effects, and you should immediately notify your doctor when you experience or notice any negative symptoms after taking the medication.
You should not take Vimovo if you are allergic to NSAIDs or any components in Vimovo. This medication may not be ideal for people with certain medical conditions. You should inform your doctor if you have intestinal/stomach/esophagus problems (such as ulcers, bleeding, or recurring heartburn), heart disease, kidney disease, liver disease, high blood pressure, blood disorders such as anemia, and clotting problems. You should also consult your doctor if you have a history of stroke, heart attack, and stomach ulcers. Women who are pregnant, plan to become pregnant, or are breastfeeding should consult their doctor before taking Vimovo.
The drug is available in the form of a tablet which comes in two strengths: Vimovo 375mg/20mg (the tablet has 375 mg of Naproxen and 20 mg of Esomeprazole) and Vimovo 500mg/20mg (the tablet has 500 mg of Naproxen and 20 mg of Esomeprazole). Doctors generally recommend a dose of two tablets in a day (one tablet of Vimovo in the morning and one tablet in the evening). The dosage should be taken as recommended by your doctor. He/she may also ask you to take the medication 30 minutes before the meal. You should not stop or change the dosage without consulting your doctor.
Vimovo may interact with other drugs and cause side effects. The drug may also not work properly after interacting with other drugs, thus defeating the objective of taking the medication. Your doctor may be aware of the possible interactions of Vimovo with other drugs, so it is important that you tell your doctor about every medicine you take, which includes prescribed, non-prescribed, and herbal medicines. Vimovo may interact with drugs such as amphetamines, anti-platelet drugs, oral bisphosphonates, blood thinner medications, antidepressants, corticosteroids, or HIV drugs.
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What is a "Generic" medication/drug?
Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price. Nearly 1 in 3 drugs dispensed are "generic". They undergo testing to ensure that they are similar to their "brand" counterparts in:
- Active Ingredient (e.g. "Pravastatin" is the active ingredient in brand name Pravachol)
- Dosage (e.g. 10 mg of the active ingredient)
- Safety (e.g. same or similar side effects, drug interactions)
- Performance (e.g. 10 mg of a "generic" can be substituted for 10 mg of the "brand" and have the same therapeutic result)
- Intended use (e.g. both "generic" and "brand" would be prescribed for the same conditions)
What this means is that "generic" medications can be used as a substitute of their brand equivalents with the comparable therapeutic results. There are a few exceptions (examples are outlined at the end of this page) and as always you should consult your physician before switching from a brand name medications to a generic or vice versa.
What differences are there between generic and brand?
While generics and brand equivalent drugs contain the same active ingredients, they may be different in the following ways:
- Appearance (e.g. the scoring or markings)
The color, shape and size of the medication come from the fillers that are added to the active ingredients to make the drug. These fillers that are added to the drug have no medical use and do not to change the effectiveness of the final product. A generic drug must contain comparable active ingredients and must have a comparable strength and dosage as the original brand name equivalent. Generic drugs can be more cost effective than purchasing the brand name.
Why do generics cost less than the brand name equivalents?
When a new drug is "invented", the company that discovered it has a patent on it that gives them the exclusive production rights for this medication. Once the patent expires in a country, other companies can bring the product to market under their own name. This patent prevents other companies from copying the drug during that time so they can earn back their Research and Development costs through being the exclusive supplier of the product. After the patent expires however, other companies can develop a "generic" version of the product. These versions generally are offered at much lower prices because the companies do not have the same development costs as the original company who developed the medication.
The main thing to realize here though is that the two products are therapeutically equivalent. They may look different, and be called something different.
How are Generic drugs tested to ensure quality and efficacy?
Generally speaking, the two most generally accepted methods to prove the safety of a generic version of a drug are to either repeat most of the chemistry, animal and human studies originally done, or to show that the drug performs comparably with the original brand name drug. This second option is called a "comparative bioavailability" study. During this type of study, volunteers are given the original drug, and then separately later the generic drug. The rates at which the drug is delivered to the patient (into their blood stream or otherwise absorbed) are measured to ensure they are the same. Because the same active ingredient is used the major concern is just that it delivers the common chemical(s) at the same rate so that they have the same effect. Please note that the methods that the manufacturers use may vary from country to country.